منابع مشابه
Inhibitor Specificity of Amine Oxidase
In their studies of the oxidation of adrenalin and other amines by amine oxidase preparations, Blaschko, Richter, and Schlossmann (1) found that l-ephedrine, triethylamine, triisoamylamine, and dl-1-hydroxy-2-hydrindeneamine are not only not oxidized, but inhibit the action of the enzyme upon isoamylamine. The conclusion was drawn that this inhibition was of the competitive type, because some d...
متن کاملSubstrate specificity of amine oxidases.
DuBois, K. P., Albaum, H. G. & Potter, V. R. (1943). J. biol. Chem. 147, 699. Green, H. N. (1943). Lancet, 2, 147. Green, H. N. & Stoner, H. B. (1944). Brit. J. exp. Path. 25, 150. Kal¢kar, H. M. (1943). J. biol. Chem. 148, 127. Kolthoff, I. M. (1932). Saure-Ba8en Indicatoren. Berlin: Springer. Krebs, H. A. & Henseleit, K. (1932). Ho.ppe-Seyl. Z. 210, 33.' Lyubimova, M. N. & Pevsner, D. (1941)....
متن کاملXanthine Oxidase. Vi. Influence of Ph on Substrate Specificity.
Milk xanthine oxidase exhibits a broad substrate specificity that includes purines, aldehydes, and pteridines (1). The mechanism of substrate oxidation, particularly that of purines, has been the subject of several studies (2-4). The present report concerns the observation of a new class of substrates, quaternary heterocyclic compounds, which are oxidized at pH values above 9.6. A partial list ...
متن کاملEngineering the substrate specificity of D-amino-acid oxidase.
The high resolution crystal structure of D-amino-acid oxidase (DAAO) from the yeast Rhodotorula gracilis provided us with the tool to engineer the substrate specificity of this flavo-oxidase. DAAO catalyzes the oxidative deamination of D-amino acids, with the exception of D-aspartate and D-glutamate (which are oxidized by D-aspartate oxidase, DASPO). Following sequence homology, molecular model...
متن کاملSpermine Oxidase: an Amine Oxidase with Specificity for Spermine and Spermidine
Sheep serum and bovine serum contain an enzyme which brings about a rapid oxidative deamination of certain biological amines. This enzyme differs from previously described amine oxidases in several regards and especially in its substrate specificity. Studies thus far indicate that only spermine and the closely related compound spermidine serve as substrates for the enzyme in sheep serum. For th...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1943
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)72344-2